Aquarium Medications; Part 2, Antibiotics/Anti-microbials

[Carl]

I've updated the "Aquarium Medications; Part 2, Antibiotics/Anti-microbials " article

www.americanaquariumproducts.com/AquariumMedication2.html

Here is an excerpt from the "blends" section:
"While many of medications can be blended, they do not have the full synergistic kick unless blended intentionally in ratios that also allow for optimum concurrent use. An example would be blending Nitrofurazone with Kanamycin Sulfate.
While using separate medications such as Furan 2 & Kanaplex can certainly be effective, blending these in optimal rations and using 100% concurrently is impossible out of the package when used as directed, which is why products such as AAP Spectrogram is the better choice.
As well many medications that were once the mainstay of aquarium keeping professionals ceased to exist but are now being brought back, such as Naladixic Acid, Wound Control/Merbromin, and Eye Fungex.

*EXAMPLE BLENDS::

AAP Spectrogram is now being brought back as a much more convenient way to utilize the Nitrofurazone/Kanamycin Sulfate wide spectrum combination treatment, especially for difficult cases of Columnaris or Aeromonas.
Resource: AAP Spectrogram; Kanamycin/Nitrofurazone Wide Spectrum Combination

AAP Discomed is the ultimate blended "feeding" antibiotic blend. This product blends ingredients that address a wide variety of internal parasitic issues, as well as osmoregulation & some internal bacterial issues/
Resource: AAP Discomed

For very serious combination bacterial/fungal/parasitic infections (such as Ichthyophonus or even virus infections such as “Angelfish aids”), especially in often difficult to treat Loach, Botia, Cory Catfish and similar fish.
This combination PLUS AAP Super Ich Plus/Greenex OR better, a Medicated Wonder Shell can often be the “kick” needed for a cure, see below.
The Medicated Wonder Shell provides the biggest kick when added to AAP Spectrogram, especially if Redox Balance is off with an aquarium that may have already been over medicated resulting in oxidative stress.
I often call this and the combinations below my "everything but the kitchen sink" treatments!

If used EXACTLY as prescribed, these are some of the better fish treatment combinations I have every used and is especially good when fish are dying suddenly for causes that are not clear.

OPTION ONE;; AAP Spectrogram can be combined & AAP Super Ich Plus (or ParaGuard) OR Medicated Wonder Shell for a strong fungal, & bacterial infection treatment.
OPTION TWO;; use Nitrofurazone (AAP Furan 2), AAP Super Ich Plus OR Medicated Wonder Shell, & Metronidazole for an excellent parasitic, fungal, & moderate bacterial infection treatment.

While this can be harsh on the aquarium system, it is generally safe for most fish and a healthy well established aquarium."



Carl

[Carl]

I've further updated this article, in particular the section dealing with Naladixic Acid
www.americanaquariumproducts.com/AquariumMedication2.html#naladixic

Here is an excerpt:
"Nalidixic Acid is a quinolone, a family of broad-spectrum antibiotics.
Nalidixic Acid (also known as Naladixic Acid and Naladin) is effective against many gram negative and some positive bacteria.
In humans it was, as the antibiotic is no longer used for humans, used for urinary tract infections.
Naladixic Acid is similar in its effectiveness to Septra (AKA Trimethoprin).

USE:
In aquariums it has been shown to be occasionally effective for swelling caused by fluids in the internal cavity of the fish that is often diagnosed as Dropsy.
It has also shown effectiveness in treating sporozoans (Pleistophora hyphessobryconis) sometimes referred to as neon tetra disease.

For this application Naladixic Acid works best combined with Metronidazole or Gentian Violet. Although for this condition I prefer a Methylene Blue bath and Metronidazole in the aquarium (or possibly AAP Super Ich Plus or ParaGuard).

Naladixic Acid is also often a good product to use for symptoms of whirling disease or unexplained fish deaths, especially when the cause is unidentified, but fish keeping dying. Combining with AAP Super Ich Plusl can be helpful with unexplained fish death use.

Caution should be used with Nalidixic Acid in hard water aquariums as high amounts of calcium will interact with this antibiotic.

Contraindications

*Use of Naladixic Acid in aquariums with higher levels of magnesium, calcium, or iron can affect effectiveness. Discontinue Wonder Shell use and planted tank GH ferts during use for best results.

Product Resources:
*AAP Naladixic Acid (Naladin)"



Carl

[Carl]

I have further updated the "Aquarium Medications Part 2; Chloramphenicol Section"
www.americanaquariumproducts.com/AquariumMedication2.html#chloramphenicol

Here is an excerpt:
"CHLORAMPHENICOL:

Chloramphenicol has in vitro activity against most anaerobic bacteria (gram positive/negative), and aerobic gram-positive bacteria making this one of the more effective antibiotics I have ever used for fish due to its wide spectrum effectiveness, especially as per many aquatic bacterial pathogens (and even some parasites too).

Unfortunately the toxicity of Chloramphenicol, which has been linked to the development of aplastic anemia (a rare but potentially fatal condition) and dose-dependent leukopenia, has made this antibiotic impossible to find for most aquarists due to strict regulation, with Kanamycin Sulfate the closest substitute.
This said, the synergistic combination found in AAP Spectrogram is more effective from my experience and in 100s of uses. In other words, there is no where that Chloramphenicol works where AAP Spectrogram does not (actually quite the opposite).
*Resource: AAP Spectrogram; Synergistic Kanamycin/Nitrofurazone Wide Spectrum Combination"



Carl